Obsada:

• Carlos Boyero Himself
• Montxo Armendáriz Himself
• Juan José Ballesta Himself
• Tristán Bauer Himself
• Fabián Bielinsky Himself
• Javier Cámara Himself
• Joan Chen Herself
• Willem Dafoe Himself
• Ricardo Darín Himself
• Chema de la Peña Himself
• Milos Forman Himself
• Ben Gazzara Himself
• Terry Gilliam Himself
• Anjelica Huston
• Pilar López de Ayala Maestra
• Manuel Martín Cuenca Himself
• Gastón Pauls Himself
• Nathalie Poza Ana
• Alberto Rodríguez Himself
• Bohdan Sláma Himself
• Gabriel Velázquez Himself
• Leonor Watling Herself
• Michael Winterbottom Himself
• Yang Zhang Himself
• Gillian Anderson Widow Wadman
• Kathy Bates Annie Wilkes
• Timy Benito Javi
• Richard Beymer Toni
• Juan Diego Botto Miguel
• Jeff Bridges Noah
• Críspulo Cabezas Rai
• Héctor Colomé Ismael
• Steve Coogan Tristram Shandy / Walter Shandy
• Geena Davis Thelma
• Jodelle Ferland Jeliza-Rose
• Florentino Fernández Disi
• Mariola Fuentes Juanita Narboni
• Lluís Homar Esteban adulto
• Bárbara Lennie Lourdes
• Steve McQueen Jake Holman
• Joaquín Sabina Himself
• Mercedes Sampietro Madre de Miguel
• Susan Sarandon Louise
• Santiago Segura Isi
• Hilary Swank Teena Brandon - Brandon Teena
• Luis Tosar Pablo López
• María Valverde María
• Natalie Wood Maria
• Eloi Yebra Manu