Obsada:

• Tony Jay Narrator
• Harold Schechter Author "Depraved" Himself
• Thomas Cronin Criminal Profiler Himself
• Marian Caporusso Herself, Programs Section Chief, Illinois State Police Forensic Science Center
• Ed Bertagnoli Chicago Police Officer
• Cary Callison Chicago Detective
• Willy Laszlo H.H. Holmes
• Rachelle Villarreal Alice Pitezel
• Audrey Welling Castle Victim
• Beka Beka Carrie Pitezel
• Tom Ciappa
• Sarah Mills
• H.H. Holmes Himself