Obsada:

• Seth MacFarlane Stewie Griffin / Peter Griffin / Brian Griffin / Glen Quagmire / Tom Tucker / Stuart 'Stu' Griffin / Bugs Bunny / Kool-Aid Guy / Additional Voices
• Alex Borstein Lois Griffin / Tricia Takanawa / Vanessa / Condoleezza Rice / Additional Voices
• Seth Green Chris Griffin / Additional Voices
• Mila Kunis Meg Griffin / Additional Voices
• Lori Alan Diane Simmons
• Drew Barrymore Herself
• Noel Blanc Elmer Fudd / Additional Voices
• John G. Brennan Horace / Additional Voices
• Mike Henry Cleveland Brown / Herbert
• Gary Janetti
• Don LaFontaine FOX Announcer
• Phil LaMarr Ollie Williams / Additional Voices
• Ron Livingston Clerk
• Rachael MacFarlane Katie Couric / Baby-Expecting Woman
• Kevin Michael Richardson Ray Charles / Additional Voices
• Kate Rigg
• Will Sasso Randy Newman / James Lipton
• André Sogliuzzo
• Rory Thost Casper
• John Viener Meg 'Ron' Griffin
• Adam West Himself - Mayor
• Wally Wingert Additional Voices
• Rene Auberjonois Odo
• Ralph Garman
• Jennie Garth Kelly Taylor
• Larry Kenney Lion-O
• Lynne Lipton Cheetara
• Jason Priestley Brandon Walsh
• Chris Sheridan
• Danny Smith
• Tori Spelling Donna Martin
• Fred Tatasciore
• Adam Borstein
• Joy Behar Herself
• Michael Clarke Duncan The Stork
• Bill Fagerbakke Indian
• David A. Goodman Jesus
• Ali Hillis
• Busy Philipps
• Patrick Warburton Joe Swanson
• Audrey Wasilewski